1.1.99.B6: phosphonoacetaldehyde reductase (acceptor)

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For detailed information about phosphonoacetaldehyde reductase (acceptor), go to the full flat file.

Reaction

Synonyms

FomC

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.99 With unknown physiological acceptors

1.1.99.B6 phosphonoacetaldehyde reductase (acceptor)

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
1	Cofactor
1	General Information
1	kcat/KM [mM/s]
2	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
4	Organism
2	pH Optimum
1	Purification (Commentary)
1	Reaction
4	Reference
3	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Turnover Number [1/s]

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Reference on EC 1.1.99.B6 - phosphonoacetaldehyde reductase (acceptor)

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703183

Woodyer, R.D.; Li, G.; Zhao, H.; van der Donk, W.A.

New insight into the mechanism of methyl transfer during the biosynthesis of fosfomycin

Chem. Commun. (Camb. )

359-361

2007

Streptomyces fradiae (D2SNG2)

17220970

705742

Hidaka, T.; Goda, M.; Kuzuyama, T.; Takei, N.; Hidaka, M.; Seto, H.

Cloning and nucleotide sequence of fosfomycin biosynthetic genes of Streptomyces wedmorensis

Mol. Gen. Genet.

249

274-280

1995

Streptomyces wedmorensis (P96075), Streptomyces wedmorensis 144-91 (P96075)

7500951

712363

Shao, Z.; Blodgett, J.A.V.; Circello, B.T.; Eliot, A.C.; Woodyer, R.; Li, G.; van der Donk, W.A.; Metcalf, W.W.; Zhao, H.

Biosynthesis of 2-hydroxyethylphosphonate, an unexpected intermediate common to multiple phosphonate biosynthetic pathways

J. Biol. Chem.

283

23161-23168

2008

Streptomyces wedmorensis

18544530