1.1.99.39: D-2-hydroxyglutarate dehydrogenase
This is an abbreviated version!
For detailed information about D-2-hydroxyglutarate dehydrogenase, go to the full flat file.
Word Map on EC 1.1.99.39
-
1.1.99.39
-
acidurias
-
neurometabolic
-
isocitrate
-
2-ketoglutarate
-
l2hgdh
-
l-2-hga
-
d-lactate
-
d-malate
-
chondromatosis
-
metaphyseal
-
oncometabolite
- 1.1.99.39
-
acidurias
-
neurometabolic
- isocitrate
- 2-ketoglutarate
- l2hgdh
-
l-2-hga
- d-lactate
- d-malate
- chondromatosis
-
metaphyseal
-
oncometabolite
Reaction
Synonyms
2-hydroxyglutarate dehydrogenase, AtD-2HGDH, D-2-HG dehydrogenase, D-2-HGA, D-2-hydroxyglutarate dehydrogenase, D2-hydroxyglutarate dehydrogenase, D2HDH, D2HGDH
ECTree
Advanced search results
Natural Substrates Products
Natural Substrates Products on EC 1.1.99.39 - D-2-hydroxyglutarate dehydrogenase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REACTION DIAGRAM
(R)-2-hydroxyglutarate + electron transfer flavoprotein
2-oxoglutarate + reduced electron transfer flavoprotein
(S)-2-hydroxyglutarate + acceptor
2-oxoglutarate + reduced acceptor
necessary step in the serine biosynthetic pathway
-
-
?
additional information
?
-
-
description of two pathogenic mutations in the D-2-hydroxyglutarate dehydrogenase gene causing D-2-HGA with a very mild clinical presentation: a splice error (IVS4-2A->G) and a missense mutation (c.1315A->G, p.Asn439Asp). Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause bith the severe and mild phenotypes of D-2-HGA
-
-
?
2-oxoglutarate + reduced acceptor
-
-
-
-
?
(R)-2-hydroxyglutarate + acceptor
2-oxoglutarate + reduced acceptor
-
-
-
?
(R)-2-hydroxyglutarate + acceptor
2-oxoglutarate + reduced acceptor
-
-
-
?
(R)-2-hydroxyglutarate + acceptor
2-oxoglutarate + reduced acceptor
-
-
-
-
?
(R)-2-hydroxyglutarate + acceptor
2-oxoglutarate + reduced acceptor
-
-
-
-
?
2-oxoglutarate + reduced electron transfer flavoprotein
-
-
-
?
(R)-2-hydroxyglutarate + electron transfer flavoprotein
2-oxoglutarate + reduced electron transfer flavoprotein
-
-
-
-
?
(R)-2-hydroxyglutarate + electron transfer flavoprotein
2-oxoglutarate + reduced electron transfer flavoprotein
-
-
-
-
?