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1.1.99.1: choline dehydrogenase

This is an abbreviated version!
For detailed information about choline dehydrogenase, go to the full flat file.

Word Map on EC 1.1.99.1

Reaction

choline
+
acceptor
=
Betaine aldehyde
 +
reduced acceptor

Synonyms

Cdh, CHD, CHDH, ChoDH, choline dehydrogenase, choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, dehydrogenase, choline, oxidase, choline

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.99 With unknown physiological acceptors
                1.1.99.1 choline dehydrogenase

Inhibitors

Inhibitors on EC 1.1.99.1 - choline dehydrogenase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-Dimethylaminoethanol
-
-
3,3-dimethylbutanol
completely blocks activity
-
AgNO3
-
1 mM causes 100% inhibition
Benzyltrimethylammonium chloride
-
slight
Betaine aldehyde
-
choline dehydrogenase activity
Betaine hydrochloride
-
slight
CuSO4
-
1 mM causes 100% inhibition
dimethylglycine
-
slight
DL-3-hydroxybutyrate
-
at 16.7 mM acts as weak inhibitor
DL-Carnitine hydrochloride
-
slight
glycine
-
slight
HgCl2
-
1 mM causes 100% inhibition
iodoacetic acid
-
-
KCN
-
1 mM inhibits
Mercuric acetate
-
-
MnCl2
-
1 mM causes 100% inhibition
Monoethanolamine
-
-
NaCN
-
1 mM inhibits
p-chloromercuribenzoate
-
-
Phenyltriethylammonium iodide
-
slight
Semicarbazide
Tetra-n-butylammonium iodide
-
slight
Tetra-n-propylammonium iodide
-
slight
Tetraethylammonium iodide
-
slight
Tetramethylammonium iodide
-
slight
Triethylbenzylammonium iodide
-
slight
additional information
-
the enzyme expression is not affected by methionine or choline intake in liver, overview
-