1.1.99.1: choline dehydrogenase

This is an abbreviated version!
For detailed information about choline dehydrogenase, go to the full flat file.

Reaction

Synonyms

Cdh, CHD, CHDH, ChoDH, choline dehydrogenase, choline oxidase, choline-cytochrome c reductase, choline:(acceptor) oxidoreductase, dehydrogenase, choline, oxidase, choline

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.99 With unknown physiological acceptors

                1.1.99.1 choline dehydrogenase

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Results	in table
3	Activating Compound
12267	AA Sequence
3	Application
1	CAS Registry Number
9	Cloned(Commentary)
12	Cofactor
53	Disease/ Diagnostics
1	Expression
18	General Information
6	General Stability
28	Inhibitors
2	Ki Value [mM]
11	KM Value [mM]
18	Localization
1	Metals/Ions
6	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
33	Organism
6	Pathway
6	pH Optimum
2	pH Range
2	pH Stability
1	pI Value
1	Posttranslational Modification
3	Protein Variants
8	Purification (Commentary)
3	Reaction
3	Reaction Type
29	Reference
31	Source Tissue
7	Specific Activity [micromol/min/mg]
7	Storage Stability
66	Substrates and Products (Substrate)
9	Subunits
21	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
5	Temperature Stability [°C]

General Stability

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General Stability on EC 1.1.99.1 - choline dehydrogenase

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GENERAL STABILITY

ORGANISM

UNIPROT

LITERATURE

25 cycles of freezing/thawing cause 40% loss of activity

Rattus norvegicus

-

389884

detergents, e.g. Brij 58, Triton X-100, cholate, deoxycholate or beta-octylglucoside stabilize

Canis lupus familiaris

-

389883

glycerol, 30%, stabilizes partially purified enzyme

Rattus norvegicus

-

389885

high instability of the enzyme once it is removed from the inner mitochondrial membrane

2 entries

repeated freezing and thawing: rapid loss of activity

Rattus norvegicus

-

389886

high instability of the enzyme once it is removed from the inner mitochondrial membrane

Rattus norvegicus

Q6UPE0

741756

high instability of the enzyme once it is removed from the inner mitochondrial membrane

Homo sapiens

Q8NE62

741756