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1.1.3.7: aryl-alcohol oxidase

This is an abbreviated version!
For detailed information about aryl-alcohol oxidase, go to the full flat file.

Word Map on EC 1.1.3.7

Reaction

an aromatic primary alcohol
+
O2
=
an aromatic aldehyde
+
H2O2

Synonyms

AAO, AAO2, AAOx, alcohol: O2 oxidoreductase, AOX, arom. alcohol oxidase, aryl alcohol oxidase, arylalcohol oxidase, CpSAO, CtSAO, GaoB, GLRG_02805, GMC oxidoreductase-like protein, HMFO, More, MtGloA, MYCTH_2299749, oxidase, aryl alcohol, salicyl alcohol oxidase, um04044, VAO, veratryl alcohol oxidase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.3 With oxygen as acceptor
                1.1.3.7 aryl-alcohol oxidase

Inhibitors

Inhibitors on EC 1.1.3.7 - aryl-alcohol oxidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-hydroxybenzyl alcohol
3-Phenyl-1-propanol
4-anisic acid
4-Hydroxybenzyl alcohol
-
shows substrate inhibition at higher concentration
4-methoxybenzylamine
-
uncompetitive, pH-dependent inhibition, best at pH 8.0
Ag+
-
0.5 mM, 38% inhibition
anisyl alcohol
-
shows substrate inhibition at higher concentration
benzylmethyl ether
-
competitive
CaCl2
-
15% inhibition at 0.5 mM
chavicol
-
competitive
cinnamyl alcohol
-
shows substrate inhibition at higher concentration
dithiothreitol
-
7% inhibition at 0.5 mM
EDTA
-
24% inhibition at 0.5 mM
H2O2
inhibitory to the oxidation of formylfurancarboxylic acid, oxidation activities of AAO on 5-hydroxymethylfurfural and 2,5-diformylfuran are independent of the presence of H2O2
HgCl2
-
1 mM, 92% inhibition
L-cysteine
-
20% inhibition at 0.5 mM
MgCl2
-
16% inhibition at 0.5 mM
MnCl2
-
14% inhibition at 0.5 mM
NaN3
-
10 mM, 19% inhibition
p-methoxybenzyl alcohol
-
substrate inhibition at high concentrations
Pb2+
-
0.5 mM, 63% inhibition
PCMB
-
1 mM, 95% inhibition
phenol
-
competitive
Sodium azide
-
mixed competitive inhibition, 90% inhibition at 0.5 mM
Toluene
-
competitive
ZnSO4
-
8% inhibition at 0.5 mM
additional information
-