1.1.1.B38: hydroxymethylglutaryl-CoA reductase [NAD(P)H]
This is an abbreviated version!
For detailed information about hydroxymethylglutaryl-CoA reductase [NAD(P)H], go to the full flat file.
Reaction
+ + 2 NAD(P)+ = + 2 NAD(P)H + 2 H+
Synonyms
3-hydroxy-3-methylglutaryl coenzyme A reductase, AF1736, class II HMG-CoA reductase, HGMR, HMG-CoA reductase
ECTree
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Cofactor
Cofactor on EC 1.1.1.B38 - hydroxymethylglutaryl-CoA reductase [NAD(P)H]
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NAD+
slight preference for NAD(H) versus NADP(H). Optimal activity using NADP(H) occurrs at a pH from 1 to 3 units more acidic than that observed using NAD(H). Each coenzyme acts as a competitive inhibitor of the other
NADP+
slight preference for NAD(H) versus NADP(H). Optimal activity using NADP(H) occurrs at a pH from 1 to 3 units more acidic than that observed using NAD(H). Each coenzyme acts as a competitive inhibitor of the other
NADH
slight preference for NAD(H) versus NADP(H). Optimal activity using NADP(H) occurrs at a pH from 1 to 3 units more acidic than that observed using NAD(H). Each coenzyme acts as a competitive inhibitor of the other
slight preference for NAD(H) versus NADP(H). Optimal activity using NADP(H) occurrs at a pH from 1 to 3 units more acidic than that observed using NAD(H). Each coenzyme acts as a competitive inhibitor of the other