1.1.1.67: mannitol 2-dehydrogenase
This is an abbreviated version!
For detailed information about mannitol 2-dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.67
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1.1.1.67
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polyol
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fluorescens
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d-fructose
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synthesis
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5-dehydrogenase
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1.1.1.138
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heterofermentative
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reuteri
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gluconobacter
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industry
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pfldh
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arabitol
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molasses
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nutrition
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biotechnology
-
analysis
- 1.1.1.67
-
polyol
- fluorescens
- d-fructose
- synthesis
-
5-dehydrogenase
-
1.1.1.138
-
heterofermentative
- reuteri
- gluconobacter
- industry
- pfldh
- arabitol
- molasses
- nutrition
- biotechnology
- analysis
Reaction
Synonyms
alcohol dehydrogenase, zinc-containing, D-mannitol dehydrogenase, M2DH, mannitol 2-dehydrogenase, mannitol dehydrogenase, mannitol-2-dehydrogenase, MDH, mt-dh, MtDH, MtlD, NAD+-dependent mannitol dehydrogenase, NADH-dependent mannitol dehydrogenase, pfMDH, polyol dehydrogenase, PsM2DH, TM0298, TM_0298
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Metals Ions
Metals Ions on EC 1.1.1.67 - mannitol 2-dehydrogenase
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Co2+
Zn2+
additional information
Co2+
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addition of Co2+ restores activity of the zinc-dependent enzyme after inhibition by EDTA
Zn2+
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required, MtDH contains a single Zn2+ atom, and no additional metals have been found in this enzyme
additional information
20 mM MgCl2 or CaCl2 do not increase the activity of the EDTA-treated enzyme
additional information
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20 mM MgCl2 or CaCl2 do not increase the activity of the EDTA-treated enzyme
additional information
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the Cys91, Cys94, Cys97, and Cys105 residues at the enzyme active site are either bare or have non-functional metal binding. Thermotoga maritima MtDH activity is restored after EDTA treatment by the addition of Co2+ better than Zn2+