1.1.1.64: testosterone 17beta-dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about testosterone 17beta-dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.64

1.1.1.64

androgen

testis

17beta-hsd3

androstenedione

testicular

leydig

hsd17b3

steroidogenic

puberty

5alpha-reductase

pseudohermaphroditism

genitalia

dehydrogenase-3

estrone

p450scc

medicine

drug development

diagnostics

Reaction

Synonyms

17-ketoreductase, 17beta-HSD, 17beta-HSD 3, 17beta-HSD type 3, 17beta-HSD type 5, 17beta-HSD-3, 17beta-HSD1, 17beta-HSD3, 17beta-HSD4, 17beta-HSD5, 17beta-hydroxysteroid dehydrogenase, 17beta-hydroxysteroid dehydrogenase 3, 17beta-hydroxysteroid dehydrogenase type 3, 17beta-hydroxysteroid dehydrogenase type 5, 17beta-hydroxysteroid dehydrogenases type 3, 17betaHSD3, 3beta-hydroxysteroid dehydrogenase type 3, AKR1C3, HSD17B3, More, NADP-dependent testosterone-17beta-oxidoreductase, type 3 17beta-HSD, type 3 17beta-hydroxysteroid dehydrogenase, type 5 17beta-hydroxysteroid dehydrogenase, type 5 beta-hydroxysteroid dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)

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Results	in table
1	Activating Compound
24	AA Sequence
5	Application
1	CAS Registry Number
12	Cloned(Commentary)
57	Cofactor
6	Crystallization (Commentary)
31	Disease/ Diagnostics
5	Expression
17	General Information
1	General Stability
114	IC50 Value
231	Inhibitors
1	kcat/KM [mM/s]
12	Ki Value [mM]
31	KM Value [mM]
23	Localization
9	Molecular Weight [Da]
55	Natural Substrates/ Products (Substrates)
65	Organism
7	Pathway
52	PDB ID
12	pH Optimum
2	pH Range
16	Protein Variants
7	Purification (Commentary)
3	Reaction
3	Reaction Type
65	Reference
78	Source Tissue
7	Specific Activity [micromol/min/mg]
2	Storage Stability
112	Substrates and Products (Substrate)
1	Subunits
65	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.64 - testosterone 17beta-dehydrogenase (NADP+)

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17beta-estradiol + NADP+

estrone + NADPH

19 entries

5beta-androstane-3alpha,17beta-diol + NADP+

5beta-androstane-3alpha-ol-17-one + NADPH + H+

Mus musculus

287192

androst-4-ene-3,17-dione + NADPH

testosterone + NADP+

2 entries

androstenedione + NADPH + H+

testosterone + NADP+

5 entries

testosterone + NAD+

androst-4-ene-3,17-dione + NADH + H+

Sus scrofa

NADP+ is preferred

287225

testosterone + NADP+

androst-4-ene-3,17-dione + NADPH + H+

19 entries

testosterone + NADP+

androstenedione + NADPH + H+

6 entries