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1.1.1.392: 3alpha-hydroxycholanate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about 3alpha-hydroxycholanate dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.392

Reaction

lithocholate
+
NADP+
=
3-oxo-5beta-cholan-24-oate
+
NADPH
+
H+

Synonyms

3alpha-HSDH, alpha-hydroxy-cholanate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.392 - 3alpha-hydroxycholanate dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
12alpha-hydroxy-3-oxo-5beta-cholan-24-oic acid + NADH + H+
3alpha,12alpha-dihydroxy-5beta-cholan-24-oic acid + NAD+
show the reaction diagram