1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating)

This is an abbreviated version!
For detailed information about malate dehydrogenase (oxaloacetate-decarboxylating), go to the full flat file.

Word Map on EC 1.1.1.38

1.1.1.38

glucose-6-phosphate

lipogenic

phosphoenolpyruvate

lipogenesis

isocitrate

adipose

citrate

thyroid

acetyl-coa

carboxykinase

co2

6-phosphogluconate

cholesterol

triglyceride

succinate

nadp+

1.1.1.40

triiodothyronine

l-malate

tricarboxylic

nadp+-dependent

6-phosphate

pentose

nadp-malic

nadp-me

atp-citrate

triacylglycerols

pigeon

fumarate

oleaginous

nadp-linked

anaplerotic

mesophyll

refeeding

pepck

phosphoglucomutase

refeed

oxalacetate

alpha-glycerophosphate

dikinase

nadph-generating

ascaris

panicum

nadp-isocitrate

crassulacean

circinelloides

hydrogenosomal

5'-deiodinase

mortierella

alpina

Reaction

Synonyms

m-NAD(P)-ME, maeA, malic enzyme, malic enzyme 2, ME2, MHD, mitochondrial malic enzyme ME2, mitochondrial NAD(P) malic enzyme, mitochondrial NAD(P) malic enzyme ME2, mitochondrial NAD(P)+-dependent malic enzyme, mitochondrial NAD-malic enzyme, NAD+-dependent malic enzyme, NAD-dependent ME, NAD-malic enzyme, NAD-ME, NAD-specific malic enzyme, NADH-dependent malic enzyme, pyruvic-malic carboxylase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
28	Activating Compound
6935	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
65	Cofactor
368	Disease/ Diagnostics
6	General Information
67	Inhibitors
16	kcat/KM [mM/s]
85	KM Value [mM]
20	Localization
18	Metals/Ions
16	Molecular Weight [Da]
98	Natural Substrates/ Products (Substrates)
56	Organism
1	Oxidation Stability
9	Pathway
34	PDB ID
20	pH Optimum
1	pH Range
15	Protein Variants
10	Purification (Commentary)
2	Reaction
4	Reaction Type
56	Reference
17	Source Tissue
27	Specific Activity [micromol/min/mg]
4	Storage Stability
155	Substrates and Products (Substrate)
2	Subunits
31	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
1	Temperature Stability [°C]
25	Turnover Number [1/s]

Activating Compound

print visible entries

print all entries

Activating Compound on EC 1.1.1.38 - malate dehydrogenase (oxaloacetate-decarboxylating)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Activating Compound Search

5,5'-dithiobis(2-nitrobenzoic acid)

Escherichia coli

0.5 mM, 2.7fold increase in oxaloacetate reduction activity

286689

alpha-methyl-DL-aspartate

1.35fold activation

aspartate

ATP

68% activation, 2 mM ATP, 0.005 mM CoA, 5 mM malate, 2 mM NAD+, 4 mM Mn2+

286683

beta-methyl-DL-aspartate

1.34fold activation

CoA

D-Aspartate

2 mM, 1.27fold activation

fumarate

L-aspartate

N-ethylmaleimide

1 mM, 8.9fold increase in oxaloacetate reduction activity

286689

NH4+

Sinorhizobium meliloti

30 mM Na+L-malate instead of K+L-malate reduces enzyme activity to 18% in the presence of 3 mM MnCl2, activity is restored with 5 or 50 mM NH4Cl

286677

p-chloromercuribenzoate

Escherichia coli

0.02 mM, 2.5fold increase in oxaloacetate reduction activity

286689

phosphoenolpyruvate

Saccharomyces cerevisiae

0.5 mM

succinate

UTP

35% activation, 2 mM UTP, 0.005 mM CoA, 5 mM malate, 2 mM NAD+, 4 mM Mn2+

286683

additional information

2 entries