1.1.1.364: dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

This is an abbreviated version!
For detailed information about dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase, go to the full flat file.

Reaction

Synonyms

GerKI

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

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Results	in table
95	AA Sequence
1	Cloned(Commentary)
1	Cofactor
1	General Information
1	Metals/Ions
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
6	Pathway
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
1	Synonyms
1	Systematic Name

Systematic Name

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Systematic Name on EC 1.1.1.364 - dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase

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SYSTEMATIC NAME

IUBMB Comments

dTDP-6-deoxy-alpha-D-allose:NAD(P)+ oxidoreductase

The enzyme forms an activated deoxy-alpha-D-allose, which is converted to mycinose after attachment to the aglycones of several macrolide antibiotics, including tylosin, chalcomycin, dihydrochalcomycin, and mycinamicin II.