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1.1.1.358: 2-dehydropantolactone reductase

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase, go to the full flat file.

Word Map on EC 1.1.1.358

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

CduCPR, conjugated polyketone reductase, conjugated polyketone reductase C2, CorCPR, CPR, CPR-01, CPR-C1, CPR-C2, ketopantoyl-lactone reductase, NADPH-dependent conjugated polyketone reductase, NADPH-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.358 2-dehydropantolactone reductase

Substrates Products

Substrates Products on EC 1.1.1.358 - 2-dehydropantolactone reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1-methylisatin + NADPH + H+
?
show the reaction diagram
-
86% of the activity compared to isatin
-
-
?
2-dehydropantolactone + NADPH + H+
(R)-pantolactone + NADP+
show the reaction diagram
5-methylisatin + NADPH + H+
?
show the reaction diagram
-
108% of the activity compared to isatin
-
-
?
camphorquinone + NADPH + H+
?
show the reaction diagram
-
97% of the activity compared to isatin
-
-
?
isatin + NADPH + H+
?
show the reaction diagram
-
-
-
-
?
additional information
?
-