1.1.1.355: 2'-dehydrokanamycin reductase

This is an abbreviated version!
For detailed information about 2'-dehydrokanamycin reductase, go to the full flat file.

Reaction

Synonyms

kanK

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.355 2'-dehydrokanamycin reductase

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21	AA Sequence
1	Cloned(Commentary)
1	Cofactor
1	Natural Substrates/ Products (Substrates)
1	Organism
5	Pathway
1	Purification (Commentary)
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 1.1.1.355 - 2'-dehydrokanamycin reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

2'-dehydrokanamycin A + NADPH + H+

kanamycin A + NADP+

Streptomyces kanamyceticus

Q2MFU6

the enzyme is involved in the conversion of kanamycin B to kanamycin A. Kanamycin is a clinically important aminoglycoside antibiotic

721287

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