1.1.1.326: zerumbone synthase
This is an abbreviated version!
For detailed information about zerumbone synthase, go to the full flat file.
Reaction
Synonyms
ZSD1
ECTree
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General Information on EC 1.1.1.326 - zerumbone synthase
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
evolution
metabolism
ZSD1 is an alcohol dehydrogenase capable of catalyzing the final step of zerumbone biosynthesis, but ZSD1 is also be involved in other biological processes
physiological function
additional information
the enzyme contains an active site sequence 155Y-X-X-X-K159, Ser142 completes the Ser-Tyr-Lys triad responsible for the catalysis of ZSD1
evolution
ZSD1 is a member of the short-chain dehydrogenase/reductase superfamily, SDR, and shares high identities with other plant SDRs involved in secondary metabolism, stress responses and phytosteroid biosynthesis
evolution
the enzyme belongs to the short-chain dehydrogenase enzyme superfamily
physiological function
ZSD1 is involved in secondary metabolism, stress responses and phytosteroid biosynthesis
physiological function
the enzyme catalyzes the biosynthesis of zerumbone, a monocyclic sesquiterpenoid ketone with potential anti-inflammatory and anti-carcinogenic effects and also potential applications in obesity prevention and treatment
