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1.1.1.268: 2-(R)-hydroxypropyl-CoM dehydrogenase

This is an abbreviated version!
For detailed information about 2-(R)-hydroxypropyl-CoM dehydrogenase, go to the full flat file.

Reaction

2-(R)-hydroxypropyl-CoM
+
NAD+
=
2-oxopropyl-CoM
+
NADH
+
H+

Synonyms

(R)-hydroxypropyl-coenzyme M dehydrogenase, (R)-hydroxypropylthioethanesulfonate dehydrogenase, 2-(2-(R)-hydroxypropylthio)ethanesulfonate dehydrogenase, 2-(R)-hydroxypropyl-coenzyme M dehydrogenase, R-HPCDH, xecD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.268 2-(R)-hydroxypropyl-CoM dehydrogenase

Turnover Number

Turnover Number on EC 1.1.1.268 - 2-(R)-hydroxypropyl-CoM dehydrogenase

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.98
(2R)-2-butanol
recombinant enzyme, pH and temperature not specified in the publication
-
1.8
(2R)-2-heptanol
recombinant enzyme, pH and temperature not specified in the publication
-
2.7
(2R)-2-hexanol
recombinant enzyme, pH and temperature not specified in the publication
-
26.8
(2R)-2-hydroxypropyl-CoM
recombinant enzyme, pH and temperature not specified in the publication
-
1.7
(2R)-2-octanol
recombinant enzyme, pH and temperature not specified in the publication
-
1.1
(2R)-2-pentanol
recombinant enzyme, pH and temperature not specified in the publication
-
2.2
(2S)-2-butanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.044
(2S)-2-hydroxypropyl-CoM
recombinant enzyme, pH and temperature not specified in the publication
2.9
(2S)-2-pentanol
recombinant enzyme, pH and temperature not specified in the publication
-
0.98 - 1.9
(R)-2-butanol
1.8
(R)-2-heptanol
-
pH 7.5, 30°C
2.7
(R)-2-hexanol
-
pH 7.5, 30°C
1.7
(R)-2-octanol
-
pH 7.5, 30°C
1.1
(R)-2-pentanol
-
pH 7.5, 30°C
2.2 - 9.3
(S)-2-butanol
2.9
(S)-2-pentanol
-
pH 7.5, 30°C
0.29 - 0.55
2-(2-hydroxyethylthio)ethanesulfonate
1.4 - 27.9
2-(2-ketopropylthio)ethanesulfonate
25.8 - 49
2-(R)-hydroxypropyl-CoM
0.12
2-(S)-hydroxypropyl-CoM
pH 7.5, 30°C
0.012 - 0.033
2-butanone
24.5 - 29
2-oxopropyl-CoM
2.9
2-propanol
26.8
2-[(R)-2-hydroxypropylthio]ethanesulfonate
-
pH 7.5, 30°C
0.044
2-[(S)-2-hydroxypropylthio]ethanesulfonate
-
pH 7.5, 30°C