1.1.1.196: 15-hydroxyprostaglandin-D dehydrogenase (NADP+)

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For detailed information about 15-hydroxyprostaglandin-D dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.196

1.1.1.196

9-ketoreductase

swine

nad+-dependent

nadp-linked

thromboxane

monkey

nad+

medulla

dehydrogenases

Reaction

(5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate

(5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate

Synonyms

15-hydroxy PGD2 dehydrogenase, 15-hydroxy prostaglandin dehydrogenase (NADP+), dehydrogenase, 15-hydroxyprostaglandin (nicotinamide adenine dinucleotide phosphate), dehydrogenase, prostaglandin D2, NADP+-dependent 15-hydroxyprostaglandin dehydrogenase, NADP+-linked 15-hydroxyprostaglandin dehydrogenase, NADP+-linkedprostaglandin D2 dehydrogenase, NADP+-specific 15-hydroxyprostaglandindehydrogenase, NADP-PGD2 dehydrogenase, prostaglandin D2 dehydrogenase, prostaglandin-D 15-dehydrogenase (NADP+)

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)

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8	AA Sequence
1	CAS Registry Number
3	Cofactor
4	Disease/ Diagnostics
2	General Stability
10	Inhibitors
10	KM Value [mM]
8	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
4	Organism
4	Pathway
3	pH Optimum
1	pH Stability
3	Purification (Commentary)
1	Reaction
3	Reaction Type
4	Reference
5	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
16	Substrates and Products (Substrate)
3	Subunits
11	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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Natural Substrates Products on EC 1.1.1.196 - 15-hydroxyprostaglandin-D dehydrogenase (NADP+)

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prostaglandin D2 + NADP+

15-ketoprostaglandin D2 + NADPH + H+

3 entries