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1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase

This is an abbreviated version!
For detailed information about hydroxycyclohexanecarboxylate dehydrogenase, go to the full flat file.

Reaction

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate
+
NAD+
=
(1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate
+
NADH
+
H+

Synonyms

(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase, dihydroxycyclohexanecarboxylate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.166 - hydroxycyclohexanecarboxylate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(+)t-3,t-4-dihydroxycyclohexanecarboxylate + NAD+
4-hydroxy-3-oxocyclohexanecarboxylate + NADH + H+
show the reaction diagram
-
-
-
-
r
(+-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate + NAD+
(+-)t-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH
show the reaction diagram
-
-
-
?
(-)-dihydroshikimate + NAD+
? + NADH
show the reaction diagram
-
-
-
?
(-)-quinate + NAD+
3-dehydroquinate + NADH + H+
show the reaction diagram
-
-
-
r
(-)-shikimate + NAD+
(-)-3-dehydroshikimate + NADH + H+
show the reaction diagram
-
more rapidly oxidized than other acids
-
r
(-)t-3,t-4-dihydroxycyclohexanecarboxylate + NAD+
4-hydroxy-3-oxocyclohexanecarboxylate + NADH + H+
show the reaction diagram
-
-
-
-
r
(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD+
(1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH
show the reaction diagram
-
-
-
r