1.1.1.127: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

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For detailed information about 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase, go to the full flat file.

Reaction

Synonyms

2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase, 2-keto-3-deoxy-D-gluconate (3-deoxy-D-glycero-2,5-hexodiulosonic acid) dehydrogenase, 2-keto-3-deoxy-D-gluconate dehydrogenase, 2-keto-3-deoxygluconate (nicotinamide adenine dinucleotide (phosphate)) dehydrogenase, 2-keto-3-deoxygluconate 5-dehydrogenase, KduD

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.127 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

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Results	in table
3299	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
8	Cofactor
1	Crystallization (Commentary)
1	General Stability
3	Inhibitors
6	KM Value [mM]
1	Metals/Ions
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
3	Organism
6	Pathway
1	PDB ID
4	pH Optimum
3	Purification (Commentary)
1	Reaction
3	Reaction Type
3	Reference
2	Source Tissue
2	Specific Activity [micromol/min/mg]
2	Storage Stability
5	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
3	Temperature Stability [°C]
2	Turnover Number [1/s]

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Reference on EC 1.1.1.127 - 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase

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285820

Condemine, G.; Hugouvieux-Cotte-Pattat, N.; Robert-Baudouy, J.

An enzyme in the pectinolytic pathway of Erwinia chrysanthemi: 2-Keto-3-deoxygluconate oxidoreductase

J. Gen. Microbiol.

130

2839-2844

1984

Dickeya chrysanthemi

285821

Preiss, J.; Ashwell, G.

Polygalacturonic acid metabolism in bacteria. II. Formation and metabolism of 3-deoxy-D-glycero-2,5-hexodiulosonic acid

J. Biol. Chem.

238

1577-1583

1963

Pseudomonas sp.

13986017

741387

Takase, R.; Maruyama, Y.; Oiki, S.; Mikami, B.; Murata, K.; Hashimoto, W.

Structural determinants in bacterial 2-keto-3-deoxy-D-gluconate dehydrogenase KduD for dual-coenzyme specificity

Proteins

934-947

2016

Pectobacterium carotovorum subsp. carotovorum

27028675