1.1.1.103: L-threonine 3-dehydrogenase

This is an abbreviated version!
For detailed information about L-threonine 3-dehydrogenase, go to the full flat file.

Reaction

Synonyms

CLOST_1621, L-ThrDH, L-threonine dehydrogenase, More, orf382, TDG, TDH, Thr dehydrogenase, ThrDH, threonine 3-dehydrogenase, threonine dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.103 L-threonine 3-dehydrogenase

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Results	in table
3	Activating Compound
11521	AA Sequence
2	Application
1	CAS Registry Number
20	Cloned(Commentary)
49	Cofactor
9	Crystallization (Commentary)
4	Disease/ Diagnostics
3	Expression
13	General Information
1	General Stability
75	Inhibitors
32	kcat/KM [mM/s]
4	Ki Value [mM]
97	KM Value [mM]
2	Localization
50	Metals/Ions
40	Molecular Weight [Da]
46	Natural Substrates/ Products (Substrates)
108	Organism
7	Pathway
82	PDB ID
24	pH Optimum
6	pH Range
4	pH Stability
3	pI Value
1	Posttranslational Modification
40	Protein Variants
30	Purification (Commentary)
9	Reaction
1	Reaction Type
67	Reference
37	Source Tissue
36	Specific Activity [micromol/min/mg]
5	Storage Stability
129	Substrates and Products (Substrate)
27	Subunits
53	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
3	Temperature Range [°C]
13	Temperature Stability [°C]
37	Turnover Number [1/s]

pH Optimum

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pH Optimum on EC 1.1.1.103 - L-threonine 3-dehydrogenase

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3 entries

10.1

Escherichia coli K-12

wild-type enzyme

285702

10.3

2 entries

Thermococcus kodakarensis KOD1

7.5

7.8

8.2 - 8.8

8.4

Escherichia coli K-12

C38D mutant enzyme, stimulated with 5 mM Zn2+

285702

8.4 - 8.5

Staphylococcus aureus

8.5 - 8.9

8.6 - 8.7

30% activity at pH 7.5, 80% activity at pH 9.8

285717

Rattus norvegicus

crude enzyme extracts from mitochondria frozen for 14 days and dialyzed

9.5

9.8