1.1.1.10: L-xylulose reductase
This is an abbreviated version!
For detailed information about L-xylulose reductase, go to the full flat file.
Word Map on EC 1.1.1.10
-
1.1.1.10
-
stipitis
-
candida
-
pichia
-
biomass
-
pentose
-
xylulokinase
-
lignocellulosic
-
d-xylose
-
xylose-fermenting
-
hydrolysate
-
nadph-dependent
-
tenuis
-
xylose-utilizing
-
scheffersomyces
-
l-arabinose
-
hemicellulosic
-
aldo-keto
-
bioethanol
-
guilliermondii
-
aldose
-
tropicalis
-
shehatae
-
oxygen-limited
-
kluyveromyces
-
transaldolase
-
furfural
-
tannophilus
-
pachysolen
-
bagasse
-
nadph-preferring
-
reesei
-
marxianus
-
co-fermentation
-
1.1.1.21
-
xylose-assimilating
-
debaryomyces
-
arabitol
-
pharmacology
-
synthesis
- 1.1.1.10
- stipitis
- candida
- pichia
- biomass
- pentose
- xylulokinase
-
lignocellulosic
- d-xylose
-
xylose-fermenting
- hydrolysate
-
nadph-dependent
- tenuis
-
xylose-utilizing
- scheffersomyces
- l-arabinose
-
hemicellulosic
-
aldo-keto
-
bioethanol
- guilliermondii
- aldose
- tropicalis
- shehatae
-
oxygen-limited
- kluyveromyces
- transaldolase
- furfural
- tannophilus
- pachysolen
- bagasse
-
nadph-preferring
- reesei
- marxianus
-
co-fermentation
-
1.1.1.21
-
xylose-assimilating
-
debaryomyces
- arabitol
- pharmacology
- synthesis
Reaction
Synonyms
DCXR, dicarbonyl/L-xylulose reductase, L-xylulose reductase, LXR, LXR3, More, NAD(P)H-dependent xylose reductase, NADP(+)-dependent xylitol dehydrogenase, NADP(H)-preferring xylitol dehydrogenase, NADP+-dependent xylitol dehydrogenase, NADP+-linked xylitol dehydrogenase, P31h, P34H, reductase, L-xylulose, RpLXR, Rplxr3, XDH, XR, XylB, xylitol dehydrogenase, xylose reductase
ECTree
1.1.1.10 L-xylulose reductaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 1.1.1.10 - L-xylulose reductase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
1,4-dibromo-2,3-butanedione + NADPH
? + NADP+
-
dicarbonyl reductase activity
-
-
r
DL-threitol + NADP+
D-erythrulose + NADPH
-
probably identical with erythrulose reductase, EC 1.1.1.162 and diacetyl reductase, EC 1.1.1.5
-
r
1,4-dibromo-2,3-butanedione + NAD(P)H
? + NAD(P)+
dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred
-
-
r
1,4-dibromo-2,3-butanedione + NAD(P)H
? + NAD(P)+
dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred
-
-
r
1,4-dibromo-2,3-butanedione + NAD(P)H
? + NAD(P)+
dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred
-
-
r
1,4-dibromo-2,3-butanedione + NAD(P)H
? + NAD(P)+
dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred
-
-
r
1,4-dibromo-2,3-butanedione + NAD(P)H
? + NAD(P)+
dicarbonyl reductase activity, best substrate, NADPH is the preferred cofactor, forward reaction is preferred
-
-
r
D-xylulose + NADH + H+
D-arabinitol + NAD+
about 100fold lower activity compared to L-xylulose
-
-
r
D-xylulose + NADPH + H+
D-xylitol + NADP+
reductase activity
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
dicarbonyl reductase activity, NADPH is the preferred cofactor
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
dicarbonyl reductase activity, NADPH is the preferred cofactor
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
dicarbonyl reductase activity, NADPH is the preferred cofactor
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
dicarbonyl reductase activity, NADPH is the preferred cofactor
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
-
detoxification of alpha-dicarbonyl compounds
-
-
r
diacetyl + NAD(P)H
acetoin + NAD(P)+
dicarbonyl reductase activity, NADPH is the preferred cofactor
-
-
r
DL-glyceraldehyde + NADPH
dihydroxyacetone + NADP+
reductase activity, forward reaction is highly preferred
-
-
r
DL-glyceraldehyde + NADPH
dihydroxyacetone + NADP+
reductase activity, forward reaction is highly preferred
-
-
r
DL-glyceraldehyde + NADPH
dihydroxyacetone + NADP+
reductase activity, forward reaction is highly preferred
-
-
r
DL-glyceraldehyde + NADPH
dihydroxyacetone + NADP+
reductase activity, forward reaction is highly preferred
-
-
r
DL-glyceraldehyde + NADPH
dihydroxyacetone + NADP+
reductase activity, forward reaction is highly preferred
-
-
r
L-sorbose + NADPH + H+
L-sorbitol + NADP+
low activity
-
-
?
L-xylulose + NADH
L-xylitol + NAD+
part of the L-arabinose catabolism
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
part of the glucuronic acid pathway, enzyme may be involved in water reabsorption and cellular osmoregulation
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
the enzyme is involved in the uronate cycle of glucose metabolism
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
L-xylulose reductase activity
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
uronate cycle of glucose metabolism
-
-
?
L-xylulose + NADPH + H+
L-xylitol + NADP+
reductase activity
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
uronate cycle of glucose metabolism
-
-
?
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
part of the uronate cycle, involved in osmoregulation in the kidney
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
L-xylulose reductase activity
-
-
r
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
uronate cycle of glucose metabolism
-
-
?
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
xylulose reductase has about 50% higher activity during xylose consumption than during the coconsumption of glucose and xylose
-
-
?
L-xylulose + NADPH + H+
L-xylitol + NADP+
-
uronate cycle of glucose metabolism
-
-
?
L-xylulose + NADPH + H+
xylitol + NADP+
preferred substrate
-
-
r
xylitol + NADP+
L-xylulose + NADPH + H+
-
-
strain DM101 and DM122, product identification is not exact, could also be D-xylulose
?
xylitol + NADP+
L-xylulose + NADPH + H+
-
engineered enzyme with altered cofactor specificity
-
-
?
additional information
?
-
NADH-linked enzyme form, no activity with NADPH and NADP+, no activity with L-arabinitol, adonitol or ribitol, dulcitol or galactitol, D-mannitol, and D-sorbitol, no activity with D-sorbose, L-sorbose, D-psicose, and D-fructose
-
-
?
additional information
?
-
-
NADH-linked enzyme form, no activity with NADPH and NADP+, no activity with L-arabinitol, adonitol or ribitol, dulcitol or galactitol, D-mannitol, and D-sorbitol, no activity with D-sorbose, L-sorbose, D-psicose, and D-fructose
-
-
?
additional information
?
-
-
minimal reductive activity also with D-xylulose, D-erythrose and dihydroxyacetone
-
-
?
additional information
?
-
-
no substrate: D-fructose, D-sorbose, L-sorbose, xylitol, D-arabitol, L-arabitol, ribitol, D-sorbitol and galactitol
-
-
?
additional information
?
-
substrate specificity, overview
-
-
?
additional information
?
-
dicarbonyl/L-xylulose reductase is bifunctional
-
-
?
additional information
?
-
-
dicarbonyl/L-xylulose reductase is bifunctional
-
-
?
additional information
?
-
-
no activity in the mitochondrial fraction with D-xylulose, D-sorbose, L-sorbose, L-erythrulose, D-fructose, D-sorbitol, L-arabitol, D-gulitol, D-talitol
-
-
?
additional information
?
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
-
minimal oxidative activity with D-arabitol, mannitol, 1,2-propanediol and 2,3-butanediol
-
-
?
additional information
?
-
substrate specificity for dicarbonyl reductase activity, overview
-
-
?
additional information
?
-
-
the size and hydrophobicity of the amino acid residues involved in substrate recognition, i.e. Q137, L143, H146, N190, and W191, is important, mutants N190V, N190V/W191S, Q137M/L143F/H146L, and N190V/W191S/Q137M/L143F/H146L show reductive activity with 4-nitroacetophenone, 5beta-androstane-3,17-dione, 5beta-androstan-17beta-ol-3-one, and 5beta-androstane-3alpha,17beta-diol, overview
-
-
?
additional information
?
-
substrate specificity in oxidation and reduction reactions, overview. No activity with D-mannitol, D-sorbitol, D-xylose, or D-fructose as substrates. D-Xylulose is a poor substrate. Enzyme RpLXR exhibits not only a L-xylulose reductase activity but also a strong dicarbonyl reductase activity
-
-
-
additional information
?
-
-
substrate specificity in oxidation and reduction reactions, overview. No activity with D-mannitol, D-sorbitol, D-xylose, or D-fructose as substrates. D-Xylulose is a poor substrate. Enzyme RpLXR exhibits not only a L-xylulose reductase activity but also a strong dicarbonyl reductase activity
-
-
-
additional information
?
-
substrate specificity in oxidation and reduction reactions, overview. No activity with D-mannitol, D-sorbitol, D-xylose, or D-fructose as substrates. D-Xylulose is a poor substrate. Enzyme RpLXR exhibits not only a L-xylulose reductase activity but also a strong dicarbonyl reductase activity
-
-
-
additional information
?
-
-
substrate specificity in oxidation and reduction reactions, overview. No activity with D-mannitol, D-sorbitol, D-xylose, or D-fructose as substrates. D-Xylulose is a poor substrate. Enzyme RpLXR exhibits not only a L-xylulose reductase activity but also a strong dicarbonyl reductase activity
-
-
-
additional information
?
-
substrate specificity, overview. No activity with L-xylo-3-hexulose, D-sorbose, D-ribitol, D-arabitol, or L-arabitol
-
-
?
additional information
?
-
-
substrate specificity, overview. No activity with L-xylo-3-hexulose, D-sorbose, D-ribitol, D-arabitol, or L-arabitol
-
-
?
additional information
?
-
substrate specificity, overview. No activity with L-xylo-3-hexulose, D-sorbose, D-ribitol, D-arabitol, or L-arabitol
-
-
?
