Reaction catalyzed by mycoketide-CoA synthase (2.3.1.295)
+
5
+
5
+
22
NADPH
+
22
=
a mycoketide-CoA
+
10
+
10
CoA
+
22
NADP+
+
11
H2O
a medium-chain acyl-CoA
+
5 malonyl-CoA
+
5 (S)-methylmalonyl-CoA
+
22 NADPH
+
22 H+
=
a mycoketide-CoA
+
10 CO2
+
10 CoA
+
22 NADP+
+
11 H2O
