Reaction catalyzed by phthioceranic/hydroxyphthioceranic acid synthase (2.3.1.287)
8
+
palmitoyl-[(hydroxy)phthioceranic acid synthase]
+
16
NADPH
+
16
=
8
CoA
+
C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase]
+
16
NADP+
+
8
+
8
H2O
8 (S)-methylmalonyl-CoA
+
palmitoyl-[(hydroxy)phthioceranic acid synthase]
+
16 NADPH
+
16 H+
=
8 CoA
+
C40-phthioceranyl-[(hydroxy)phthioceranic acid synthase]
+
16 NADP+
+
8 CO2
+
8 H2O