Reaction catalyzed by AdoMet-dependent heme synthase (1.3.98.6)
+
2
=
+
2
+
2
+
2
Fe-coproporphyrin III
+
2 S-adenosyl-L-methionine
=
protoheme
+
2 CO2
+
2 5'-deoxyadenosine
+
2 L-methionine
