Reaction catalyzed by protein-Npi-phosphohistidine-D-mannitol phosphotransferase (2.7.1.197)

		+			=			+
	[protein]-Npi-phospho-L-histidine	+		D-mannitol[side 1]	=		[protein]-L-histidine	+		D-mannitol 1-phosphate[side 2]