Reaction catalyzed by sphingolipid 8-(E/Z)-desaturase (1.14.19.29)
+
2
+
+
2
=
+
2
+
2
H2O
a (4R)-4-hydroxysphinganine ceramide
+
2 ferrocytochrome b5
+
O2
+
2 H+
=
a (4R,8Z)-4-hydroxysphing-8-enine ceramide
+
2 ferricytochrome b5
+
2 H2O
