Reaction catalyzed by hydroxymethylglutaryl-CoA reductase [NAD(P)H] (1.1.1.B38)
+
CoA
+
2
NAD(P)+
=
+
2
NAD(P)H
+
2
mevalonate
+
CoA
+
2 NAD(P)+
=
3-hydroxy-3-methylglutaryl-CoA
+
2 NAD(P)H
+
2 H+
