Reaction catalyzed by nicotine blue oxidoreductase (1.1.1.328)
+
NAD(P)+
=
+
NAD(P)H
+
3,3'-bipyridine-2,2',5,5',6,6'-hexol
+
NAD(P)+
=
(E)-2,2',5,5'-tetrahydroxy-6H,6'H-[3,3'-bipyridinylidene]-6,6'-dione
+
NAD(P)H
+
H+
