Reaction catalyzed by amorpha-4,11-diene 12-monooxygenase (1.14.14.114)
+
3
+
3
=
+
3
+
4
H2O
amorpha-4,11-diene
+
3 O2
+
3 [reduced NADPH-hemoprotein reductase]
=
artemisinate
+
3 [oxidized NADPH-hemoprotein reductase]
+
4 H2O
