Reaction catalyzed by 16S rRNA (guanine1516-N2)-methyltransferase (2.1.1.242)

		+		guanine1516 in 16S rRNA	=			+		N2-methylguanine1516 in 16S rRNA
	S-adenosyl-L-methionine	+		guanine1516 in 16S rRNA	=		S-adenosyl-L-homocysteine	+		N2-methylguanine1516 in 16S rRNA