Reaction catalyzed by costunolide synthase (1.14.14.150)
+
+
=
+
+
2
H2O
germacra-1(10),4,11(13)-trien-12-oate
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
(+)-costunolide
+
[oxidized NADPH-hemoprotein reductase]
+
2 H2O
