Reaction catalyzed by 6-hydroxy-3-succinoylpyridine 3-monooxygenase (1.14.13.163)
+
2
NADH
+
2
+
=
+
+
2
NAD+
+
H2O
4-(6-hydroxypyridin-3-yl)-4-oxobutanoate
+
2 NADH
+
2 H+
+
O2
=
2,5-dihydroxypyridine
+
succinate semialdehyde
+
2 NAD+
+
H2O
