Reaction catalyzed by UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting) (4.2.1.115)

		=			+		H2O
	UDP-N-acetyl-alpha-D-glucosamine	=		UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose	+		H2O