Reaction catalyzed by coproporphyrinogen dehydrogenase (1.3.98.3)
+
2
=
+
2
+
2
+
2
coproporphyrinogen III
+
2 S-adenosyl-L-methionine
=
protoporphyrinogen IX
+
2 CO2
+
2 L-methionine
+
2 5'-deoxyadenosine
