Reaction catalyzed by biotin synthase (2.8.1.6)
+
sulfur-(sulfur carrier)
+
2
+
2
=
+
(sulfur carrier)
+
2
+
2
+
2
dethiobiotin
+
sulfur-(sulfur carrier)
+
2 S-adenosyl-L-methionine
+
2 reduced [2Fe-2S] ferredoxin
=
biotin
+
(sulfur carrier)
+
2 L-methionine
+
2 5'-deoxyadenosine
+
2 oxidized [2Fe-2S] ferredoxin
