Reaction catalyzed by inositol-trisphosphate 3-kinase (2.7.1.127)

	ATP	+			=		ADP	+
	ATP	+		1D-myo-inositol 1,4,5-trisphosphate	=		ADP	+		1D-myo-inositol 1,3,4,5-tetrakisphosphate