Reaction catalyzed by alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (2.4.3.8)

		+			=			+
	CMP-N-acetylneuraminate	+		alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R	=		CMP	+		alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R