Reaction catalyzed by uracil-DNA glycosylase (3.2.2.27)
5-hydroxymethyluracil-mismatched double-stranded DNA with U-G mismatch
+
H2O
=
+
double-stranded DNA with abasic site
5-hydroxymethyluracil-mismatched double-stranded DNA with U-G mismatch
+
H2O
=
5-hydroxymethyluracil
+
double-stranded DNA with abasic site