Reaction catalyzed by protein acetyllysine N-acetyltransferase (2.3.1.286)
+
NAD+
+
H2O
=
[histone H4]-L-lysine12
+
+
[histone H4]-N6-acetyl-L-lysine12
+
NAD+
+
H2O
=
[histone H4]-L-lysine12
+
2''-O-acetyl-ADP-D-ribose
+
nicotinamide
