Reaction catalyzed by uracil-DNA glycosylase (3.2.2.27)
uracil-mismatched 19 nt bubbled double-stranded DNA
+
H2O
=
+
double-stranded DNA with abasic site
uracil-mismatched 19 nt bubbled double-stranded DNA
+
H2O
=
uracil
+
double-stranded DNA with abasic site