Reaction catalyzed by ent-kaurene monooxygenase (1.14.14.86)
+
3
+
3
=
+
3
+
4
H2O
ent-sandaracopimaradiene
+
3 [reduced NADPH-hemoprotein reductase]
+
3 O2
=
ent-sandaracopimaradien-19-oic acid
+
3 [oxidized NADPH-hemoprotein reductase]
+
4 H2O
