Reaction catalyzed by tryptophan 5-halogenase (1.14.19.58), tryptophan 6-halogenase (1.14.19.59)
+
FADH2
+
chloride
+
+
=
+
FAD
+
2
H2O
anthranilamide
+
FADH2
+
chloride
+
O2
+
H+
=
5-chloro-anthranilamide
+
FAD
+
2 H2O