Reaction catalyzed by NAD+-diphthamide ADP-ribosyltransferase (2.4.2.36)

	NAD+	+			=			+		N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]
	NAD+	+		diphthamide-[translation elongation factor 2]	=		nicotinamide	+		N-(ADP-D-ribosyl)diphthamide-[translation elongation factor 2]