Reaction catalyzed by ent-kaurene monooxygenase (1.14.14.86)
+
3
NADPH
+
+
=
+
+
H2O
ent-kaur-16-ene
+
3 NADPH
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
ent-kaur-16-en-19-oate
+
[oxidized NADPH-hemoprotein reductase]
+
H2O