Reaction catalyzed by N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase (2.4.1.225)

		+			=			+
	UDP-alpha-D-glucuronate	+		N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan	=		UDP	+		beta-D-glucuronosyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-proteoglycan