Reaction catalyzed by methylenetetrahydrofolate dehydrogenase (NADP+) (1.5.1.5)
+
NADP+
=
5,10-methenyltetrahydropteroylpoly-L-glutamate
+
NADPH
+
5,10-methylenetetrahydropteroylpoly-L-glutamate
+
NADP+
=
5,10-methenyltetrahydropteroylpoly-L-glutamate
+
NADPH
+
H+
