Reaction catalyzed by [ribulose-bisphosphate carboxylase]-lysine N-methyltransferase (2.1.1.127), [histone H3]-lysine4 N-trimethyltransferase (2.1.1.354), [histone H3]-lysine9 N-trimethyltransferase (2.1.1.355), [histone H4]-N-methyl-L-lysine20 N-methyltransferase (2.1.1.362)

		+			=			+
	S-adenosyl-L-methionine	+		histone L-lysine	=		S-adenosyl-L-homocysteine	+		histone N6-methyl-L-lysine