Reaction catalyzed by tetracycline 7-halogenase (1.14.19.49)
+
FADH2
+
chloride
+
+
=
+
FAD
+
2
H2O
(4S)-tetracycline
+
FADH2
+
chloride
+
O2
+
H+
=
7-chloro-(4S)-tetracycline
+
FAD
+
2 H2O
