Reaction catalyzed by protein-Npi-phosphohistidine-D-mannose phosphotransferase (2.7.1.191), protein-Npi-phosphohistidine-D-glucose phosphotransferase (2.7.1.199)

		+			=			+
	[protein]-Npi-phospho-L-histidine	+		D-fructose[side 1]	=		[protein]-L-histidine	+		D-fructose 6-phosphate[side 2]