Reaction catalyzed by sphingolipid 8-(E/Z)-desaturase (1.14.19.29)
+
+
+
=
+
+
+
H2O
(4R)-4-hydroxysphinganine ceramide
+
ferrocytochrome b5
+
O2
+
H+
=
(4R,8E)-4-hydroxysphing-8-enine ceramide
+
(4R,8Z)-4-hydroxysphing-8-enine ceramide
+
ferricytochrome b5
+
H2O
