Reaction catalyzed by (S)-norcoclaurine synthase (4.2.1.78)

		+			=			+		H2O
	thiophen-3-ylacetaldehyde	+		dopamine	=		(1S)-1-[2-(thiophen-3-yl)ethyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol	+		H2O